1. What is Bone Marrow/Peripheral Stem Cell Transplant ?

(BMT/PBSC)

2. Why BMT is necessary for CML patient ?

3. Factors impatc BMT outcomes.

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1.What is Bone Marrow/Peripheral Stem Cell Transplant

(BMT/PBSC)?

Chemotherapy and/or radiation therapy destroy body's yellow and red bone marrow first. Then doctor re-injected some of patient's own bone marrow that has been saved and purged or uses marrow from a compatible donor to replace patient's bone marrow. For CML treatment, we prefer allogenetic BMT which means marrow or stem cell is collected from compatible donor.

2.Why BMT is necessary for CML young patient?

BMT/PBSC is the only proven treatment which can cure CML.

3.Factors impact BMT outcomes.

See explanation from National Marrow Donor Program Website.

http://www.marrow.org/MEDICAL/factors_leading_patient_outcomes.html